'''SPI''' may mean:
*SCSI Parallel Interface
*Secure._Protect._Inspect. S.P.I. Dynamics, Inc. http://www.spidynamics.com
*Security_Parameter_Index (networking)
*Serial_Peripheral_Interface (electronics)
*Service_Provider_Interface
*Simulations_Publications Inc., a board game company
*Singapore_Paranormal_Investigators
*Single Page Interface (see Single_Page_Application)
*Sisters_of_Perpetual_Indulgence, international non-profit organization raising money for AIDS projects and other community service organizations, and espousing Safer_sex and personal responsibility (www.thesisters.org)
*Society_of_the_Plastics_Industry, a trade association for the plastics industry (www.socplas.org)
*Software_in_the_Public_Interest
*Software_Patent_Institute, non-profit organization providing Prior_art in the field of software technology
*Stateful_Packet_Inspection (computer networking)
*''Sveriges_Pensionärers_Intresseparti'', political party in Sweden (SPI-Partiet)
*Swiss_Performance_Index
*System_Packet_Interface, a family of interfaces from the Optical_Internetworking_Forum
{{TLAdisambig}}