"Audiences will be able to see the world from Mike Tyson's eyes for the first time," Sony Pictures Classics topper Tom Bernard said of the doc.
Following the screening, the film's director, James Toback, introduced Tyson to a rousing standing ovation, after which they participated in a brief Q&A; with the audience.
Warren Beatty walked over to Toback and rubbed his belly afterward: "You rub this for good luck!" he said.
The star-studded crowd included Woody Harrelson, Tracy Morgan, Fox NFL Sunday analyst Michael Strahan, boxing legend Sugar Ray Leonard and director Brett Ratner.