 ISB’s Ruedi Aebersold on the Promise of Proteomics
There are biological systems that are inspiring in their complexity,
and there are systems that not only inspire awe but threaten to surpass
the pale of the imagination. The proteome of even single-cell organisms
would fall into the latter category, which leaves an insufficiency of
words to describe the complexity of the human proteome. Nonetheless,
biologists now talk about deciphering this constantly changing,
near-infinite complexity of interrelating proteins to be found in human
cells the way they talked about decoding the human genome a couple of
decades ago. And just as they needed new technologies to elucidate the
sequence of human DNA, they will assuredly need new technological
capabilities to decipher the secrets encoded in our proteome.
This effort has made proteomics the newest buzzword in molecular
biology, with entire companies and academic institutions springing up to
take on the challenge. At the leading..
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Who's
Up for Five-Year Rankings?
Which of the world’s research institutions have
garnered the most citations in recent years, and which, in particular, have
surged in the last half-decade? To find out, Science Watch examined a
special five-year subset of data from the Thomson Scientific ISI
Essential Science Indicators
Web-based evaluation tool. In the accompanying tables (below), the top ten
institutions are ranked by citations in eleven main fields of science, based on
Thomson Scientific-indexed papers published and cited between 1999 and late
2003...
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